EFFECT OF AFLATOXIN M1, "A HYDROXYLATED METABOLITE OF B1" ON SPERM CELL QUALITY OF ADULT MALE WISTAR RATS.

Dublin Core

Title

EFFECT OF AFLATOXIN M1, "A HYDROXYLATED METABOLITE OF B1" ON SPERM CELL QUALITY OF ADULT MALE WISTAR RATS.

Creator

Ibeh Isaiah Nnanna
Taidi Ekrakene
Okungbowa Mo
Otabor Florence
Omorodion Nosa Terry

Date

2019-04-25

Type

Journal Article

Zotero

Author

Ibeh Isaiah Nnanna
Taidi Ekrakene
Okungbowa Mo
Otabor Florence
Omorodion Nosa Terry

Item Type

Journal Article

DOI

10.31878/ijcrpp.2019.32.2

ISSN

2523-6709, 2523-6695

Abstract Note

The effect of aflatoxin on reproductive health takes a systematic approach as it indicates that a significant number of people living in the third world regions are exposed to these toxins due to the poor storage of grains. To expose the effects of aflatoxin M1 a hydroxylated metabolite of aflatoxin M1 Twenty four Adult male Wister rats were acclimatized and broken down into four groups, Test Group one (Two weeks exposure), Group Two ( four weeks exposure), Group Three ( Six weeks exposure) and Group Four ( Control Group). The Test Group 1, 2 and 3 were orally administered 7.2g/kg (LD50) of Aflatoxin M1 for the desired weeks of exposure and the sperm cell quality was assessed to determine the effect of Aflatoxin M1 on sperm cell quality in Adult male wister rat. The predetermined level of sperm cell quality is its ability to be motile as the motility of the sperm cell determines its viability. Group three had the highest presence of sluggishly immotile cells with very low progressive motility, followed by group, two and one, 37.5+ 9.97, 55.00+9.91, and 71.67+3.07 as against the control groups 85.8+2.17 with the highest significance at the group three which showed an extended exposure of aflatoxin m1 (p=0.05). This study links infertility and aflatoxin consumption, as the higher the doses the more spermatotoxicity is built which invariably could lead to sterility and azoospermia.

Access Date

2020-06-13 00:06:57

Date

2019-04-25

Journal Abbreviation

IJCRPP

Library Catalog

DOI.org (Crossref)

Pages

7-12

Publication Title

International Journal of Current Research in Physiology and Pharmacology (IJCRPP)

Title

EFFECT OF AFLATOXIN M1, "A HYDROXYLATED METABOLITE OF B1" ON SPERM CELL QUALITY OF ADULT MALE WISTAR RATS.

URL

https://www.sumathipublications.com/index.php/ijcrpp/article/view/250

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Citation

Ibeh Isaiah Nnanna et al., “EFFECT OF AFLATOXIN M1, "A HYDROXYLATED METABOLITE OF B1" ON SPERM CELL QUALITY OF ADULT MALE WISTAR RATS.,” Open Aceess Journals Archives, accessed December 4, 2020, https://www.oajour.info/items/show/886.

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