Evaluating serum C-reactive protein level in patients with chronic obstructive pulmonary disease – A cross-sectional study

Dublin Core

Title

Evaluating serum C-reactive protein level in patients with chronic obstructive pulmonary disease – A cross-sectional study

Creator

Karthika M
Prakash Chandra Bhardwaj
Laimayum Amarnath Sharma
Laimayum Amarnath Sharma
W Kanan
W Asoka Singh

Date

2019-10-31

Type

Journal Article

Zotero

Author

Karthika M
Prakash Chandra Bhardwaj
Laimayum Amarnath Sharma
Laimayum Amarnath Sharma
W Kanan
W Asoka Singh

Item Type

Journal Article

DOI

10.31878/ijcrpp.2019.34.1

ISSN

2523-6709, 2523-6695

Abstract Note

Abstract
Patients with the chronic obstructive pulmonary disease have ongoing systemic inflammation, which can be assessed by measuring serum  C- reactive protein.
Objective: To explore whether CRP could be used as an independent predictor of disease outcome in COPD.
Methods: A cross-sectional study was conducted among 50 COPD patients attending Respiratory Medicine outpatient services in the Regional Institute of Medical Sciences (RIMS), Imphal from January 2015 to September 2016. Patients aged 18-67 were included in the study after obtaining Ethical approval from the Research Ethics Board, RIMS, Imphal. Computerized Spirometer Helios 401 was the instrument used to measure lung volumes and capacities. BeneSpheraTM CRP Latex Slide test kit was used to estimate serum c-reactive protein.
Results and observation: The present study was conducted on fifty COPD patients in which serum CRP level showed positive correlation with COPD (p=0.002) but serum CRP level with spirometric parameters showed significant negative correlation;FEV1 (r=-0.451, p=0.001), FEV1/FVC (r=-0.617, p<0.001) and PEFR (r=-0.398, p=0.004).
Conclusion: In our study, we found an association between serum CRP level and severity of COPD and Plasma CRP may be used as a marker of prognosis in COPD as the small increase is associated with poorer prognosis in COPD.
Keywords: CRP; Chronic obstructive pulmonary disease (COPD); Imphal.

Access Date

2020-06-13 00:06:34

Date

2019-10-31

Journal Abbreviation

IJCRPP

Library Catalog

DOI.org (Crossref)

Pages

1-4

Publication Title

International Journal of Current Research in Physiology and Pharmacology (IJCRPP)

Title

Evaluating serum C-reactive protein level in patients with chronic obstructive pulmonary disease – A cross-sectional study

URL

https://sumathipublications.com/index.php/ijcrpp/article/view/300

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Citation

Karthika M et al., “Evaluating serum C-reactive protein level in patients with chronic obstructive pulmonary disease – A cross-sectional study,” Open Aceess Journals Archives, accessed October 26, 2020, https://www.oajour.info/items/show/891.

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