The potential effect of pandan wangi leaf “pandanus amaryllifolius roxb.’’ extract from Indonesia as time sleep inductor

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Title

The potential effect of pandan wangi leaf “pandanus amaryllifolius roxb.’’ extract from Indonesia as time sleep inductor

Creator

Nita Tri Sulistiyati
Riandini Aisyah
Em Sutrisna

Date

2019-10-31

Type

Journal Article

Zotero

Author

Nita Tri Sulistiyati
Riandini Aisyah
Em Sutrisna

Item Type

Journal Article

DOI

10.31878/ijcrpp.2019.34.2

ISSN

2523-6709, 2523-6695

Abstract Note

Sleep plays a role in restoring the body's biochemical and physiological processes which decrease when awake. People is not familiar yet with sleep disturbances, so they rarely seek help. Sleep disturbances can cause family problems and are at risk of fatal traffic accidents. Fragant Pandan leaves (Pandanus amaryllifolius Roxb.) contains alkaloids, saponins and flavonoids which can provide a hypnotic sedative effect. The purpose of this study was to determine the effect of fragant Pandan leaf extract (Pandanus amaryllifolius Roxb.) administration in shortening the sleep induction time of male Swiss Webster strain mice. A post-test only design experimental laboratory study was conducted with control group design. The test animals used were 25 Swiss Webster male mice divided into five groups randomly : G1 group was given distilled water, G2 was given diazepam dose 1 mg / KgBB, the G3, G4 and G5 groups were given fragant Pandan leaf extract with a dose of 4 mg/25g BB, 6 mg/25g BB and 8mg/25g BB, respectively. One Way ANOVA statistical test showed significant differences in mice sleep onset (p=0.000) between groups. The results of the Post Hoc test using LSD analysis showed that there were significant differences between positive controls with groups G3, G4 and G5. Fragrant Pandan leaf extract dose of 8 mg/g BB can shorten the time of mice sleep induction male Swiss Webster strain mice. While the dose of 4 mg/g BB cannot shorten the time of induction of sleeping mice.
Keywords: Fragant Pandan leaf extract; Hypnotic-sedative; Sleep disturbances.

Access Date

2020-06-13 00:06:34

Date

2019-10-31

Journal Abbreviation

IJCRPP

Library Catalog

DOI.org (Crossref)

Pages

5-7

Publication Title

International Journal of Current Research in Physiology and Pharmacology (IJCRPP)

Title

The potential effect of pandan wangi leaf “pandanus amaryllifolius roxb.’’ extract from Indonesia as time sleep inductor

URL

https://sumathipublications.com/index.php/ijcrpp/article/view/310

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Citation

Nita Tri Sulistiyati, Riandini Aisyah, and Em Sutrisna, “The potential effect of pandan wangi leaf “pandanus amaryllifolius roxb.’’ extract from Indonesia as time sleep inductor,” Open Aceess Journals Archives, accessed October 30, 2020, https://www.oajour.info/items/show/892.

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