“SUPPLEMENTATION OF ZINC IN ACUTE AND CHRONIC HEAT STRESS ON ANTIOXIDANT CHANGES IN WISTAR ALBINO RATS”
Dublin Core
Title
“SUPPLEMENTATION OF ZINC IN ACUTE AND CHRONIC HEAT STRESS ON ANTIOXIDANT CHANGES IN WISTAR ALBINO RATS”
Creator
Antony Madhuri Bedadala
Anthony David M
Date
2020-02-23
Type
Journal Article
Zotero
Item Type
Journal Article
DOI
10.31878/ijcrpp.2020.41.04
ISSN
2523-6709, 2523-6695
Abstract Note
ABSTRACT:
Introduction: Heat stress is a major health burden with potential health out-comes. Oxidative stress is a metabolic dysfunction that carries oxidative damage of cells and tissues. Zinc is a co-factor against oxidative stress. Aim: The present study was done to evaluate the Supplementation of zinc in acute and chronic heat stress on antioxidant changes in wistar albino rats. Methodology: 36 Wistar albino rats were selected for the study. They were divided into 2 Groups. Group A was acutely and Group B was chronically heat stressed rats and both were zinc pretreated. The Enzymatic and Non enzyme activity in them were estimated.
Results: After acute and chronic heat stress, i) there was a significant increase (P <0.001) in lipid peroxidation activity. ii) Enzymatic and Non-enzymatic antioxidants were reduced (P < 0.001) iii) Rats pretreated with zinc showed a decrease (P< 0.001) in lipid peroxidation and increase (P < 0.001) in enzymatic antioxidants (P < 0.001) and Non enzymatic antioxidants.
Key Words: antioxidants, heat stress, wistar albino rats
Introduction: Heat stress is a major health burden with potential health out-comes. Oxidative stress is a metabolic dysfunction that carries oxidative damage of cells and tissues. Zinc is a co-factor against oxidative stress. Aim: The present study was done to evaluate the Supplementation of zinc in acute and chronic heat stress on antioxidant changes in wistar albino rats. Methodology: 36 Wistar albino rats were selected for the study. They were divided into 2 Groups. Group A was acutely and Group B was chronically heat stressed rats and both were zinc pretreated. The Enzymatic and Non enzyme activity in them were estimated.
Results: After acute and chronic heat stress, i) there was a significant increase (P <0.001) in lipid peroxidation activity. ii) Enzymatic and Non-enzymatic antioxidants were reduced (P < 0.001) iii) Rats pretreated with zinc showed a decrease (P< 0.001) in lipid peroxidation and increase (P < 0.001) in enzymatic antioxidants (P < 0.001) and Non enzymatic antioxidants.
Key Words: antioxidants, heat stress, wistar albino rats
Access Date
2020-06-13 00:06:21
Date
2020-02-23
Journal Abbreviation
IJCRPP
Library Catalog
DOI.org (Crossref)
Pages
14-16
Publication Title
International Journal of Current Research in Physiology and Pharmacology (IJCRPP)
Title
“SUPPLEMENTATION OF ZINC IN ACUTE AND CHRONIC HEAT STRESS ON ANTIOXIDANT CHANGES IN WISTAR ALBINO RATS”
URL
https://www.sumathipublications.com/index.php/ijcrpp/article/view/322
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Citation
Antony Madhuri Bedadala and Anthony David M, ““SUPPLEMENTATION OF ZINC IN ACUTE AND CHRONIC HEAT STRESS ON ANTIOXIDANT CHANGES IN WISTAR ALBINO RATS”,” Open Aceess Journals Archives, accessed October 26, 2020, https://www.oajour.info/items/show/894.